LncBook Edit

Citations: 0

z-index: 0

Basic information
Short name LncBook
Full name a curated knowledgebase of human long non-coding RNAs
Description LncBook is a curated knowledgebase of human lncRNAs that features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association. The current implementation of LncBook houses a large number of 270,044 lncRNAs and includes 1,867 featured lncRNAs with 3,762 lncRNA-function associations.
URL http://bigd.big.ac.cn/lncbook
Year founded 2018
Last update & version 2018 v1.0
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Beijing Institute of Genomics, Chinese Academy of Sciences
Address No. 1 Beichen West Road, Chaoyang District, Beijing, China
City Beijing
Province/State
Country/Region China
Contact name (PI/Team) Lina Ma
Contact email (PI/Helpdesk) malina@big.ac.cn
Data information
Data object
Data type
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Keyword
Publications
  • LncBook: a curated knowledgebase of human long non-coding RNAs. [PMID: 30329098]
    Ma L, Cao J, Liu L, Du Q, Li Z, Zou D, Bajic VB, Zhang Z.

    Long non-coding RNAs (lncRNAs) have significant functions in a wide range of important biological processes. Although the number of known human lncRNAs has dramatically increased, they are poorly annotated, posing great challenges for better understanding their functional significance and elucidating their complex functioning molecular mechanisms. Here, we present LncBook (http://bigd.big.ac.cn/lncbook), a curated knowledgebase of human lncRNAs that features a comprehensive collection of human lncRNAs and systematic curation of lncRNAs by multi-omics data integration, functional annotation and disease association. In the present version, LncBook houses a large number of 270 044 lncRNAs and includes 1867 featured lncRNAs with 3762 lncRNA-function associations. It also integrates an abundance of multi-omics data from expression, methylation, genome variation and lncRNA-miRNA interaction. Also, LncBook incorporates 3772 experimentally validated lncRNA-disease associations and further identifies a total of 97 998 lncRNAs that are putatively disease-associated. Collectively, LncBook is dedicated to the integration and curation of human lncRNAs as well as their associated data and thus bears great promise to serve as a valuable knowledgebase for worldwide research communities.

    Nucleic Acids Res 2019:47(D1)

    0 Citations (from Europe PMC, 2019-07-27)

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    • Gene genome and annotation: No. 0
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of LncBook.

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Record metadata

  • Created on: 2019-03-08
    • ***ina@***c.cn [2019-03-08]
    • ***ina@***c.cn [2019-03-08]
    • ***ina@***c.cn [2019-03-08]
    • ***d@***c.cn [2019-03-08]

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