EWAS Atlas Edit

Citations: 0

z-index: 0

Basic information
Short name EWAS Atlas
Full name Epigenome-Wide Association Study Atlas
Description A knowledgebase of epigenome-wide association studies
URL http://bigd.big.ac.cn/ewas
Year founded 2018
Last update & version
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Beijing Institute of Genomics, Chinese Academy of Sciences
City Beijing
Country/Region China
Contact name (PI/Team) Zhang Zhang
Contact email (PI/Helpdesk) zhangzhang@big.ac.cn
Data information
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Data type
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  • EWAS Atlas: a curated knowledgebase of epigenome-wide association studies. [PMID: 30364969]
    Mengwei Li, Dong Zou, Zhaohua Li, Ran Gao, Jian Sang, Yuansheng Zhang, Rujiao Li, Lin Xia, Tao Zhang, Guangyi Niu, Yiming Bao, Zhang Zhang

    Epigenome-Wide Association Study (EWAS) has become increasingly significant in identifying the associations between epigenetic variations and different biological traits. In this study, we develop EWAS Atlas (http://bigd.big.ac.cn/ewas), a curated knowledgebase of EWAS that provides a comprehensive collection of EWAS knowledge. Unlike extant data-oriented epigenetic resources, EWAS Atlas features manual curation of EWAS knowledge from extensive publications. In the current implementation, EWAS Atlas focuses on DNA methylation-one of the key epigenetic marks; it integrates a large number of 329 172 high-quality EWAS associations, involving 112 tissues/cell lines and covering 305 traits, 1830 cohorts and 390 ontology entities, which are completely based on manual curation from 649 studies reported in 401 publications. In addition, it is equipped with a powerful trait enrichment analysis tool, which is capable of profiling trait-trait and trait-epigenome relationships. Future developments include regular curation of recent EWAS publications, incorporation of more epigenetic marks and possible integration of EWAS with GWAS. Collectively, EWAS Atlas is dedicated to the curation, integration and standardization of EWAS knowledge and has the great potential to help researchers dissect molecular mechanisms of epigenetic modifications associated with biological traits.

    Nucleic Acids Res 2019:47(D1)

    0 Citations (from Europe PMC, 2019-07-27)


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    • Standard ontology and nomenclature: No. 0
    • Literature: No. 0
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of EWAS Atlas.

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Record metadata

  • Created on: 2019-03-06
    • ***d@***c.cn [2019-09-09]
    • ***ina@***c.cn [2019-03-08]
    • ***d@***c.cn [2019-03-07]
    • ***d@***c.cn [2019-03-06]
    • ***d@***c.cn [2019-03-06]
    • ***d@***c.cn [2019-03-06]
    • ***d@***c.cn [2019-03-06]

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