MHCBN Edit

Citations: 124

z-index: 7.75

Basic information
Short name MHCBN
Full name
Description a curated database consisting of detailed information about Major Histocompatibility Complex (MHC) Binding, Non-binding peptides and T-cell epitopes
URL http://crdd.osdd.net/raghava/mhcbn/
Year founded
Last update & version
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Institute of Microbial Technology
Address
City
Province/State
Country/Region India
Contact name (PI/Team) Gajendra P. S. Raghava
Contact email (PI/Helpdesk) raghava@iiitd.ac.in
Data information
Data object
Data type
Database category
Major organism
Keyword
Publications
  • MHCBN 4.0: A database of MHC/TAP binding peptides and T-cell epitopes. [PMID: 19379493]
    Sneh Lata, Manoj Bhasin, Gajendra P S Raghava

    BACKGROUND: Many databases housing the information about MHC binders and non-binders have been developed in the past to help the scientific community working in the field of immunology, immune-informatics or vaccine design. As the information about these MHC binding and non-binding peptides continues to grow with the time and there is a need to keep the databases updated. So, in order to provide the immunological fraternity with the most recent information we need to maintain and update our database regularly. In this paper, we describe the updated version of 4.0 of the database MHCBN.
    FINDINGS: MHCBN is a comprehensive database comprising over 25,857 peptide sequences (1053 TAP binding peptides), whose binding affinity with either MHC or TAP molecules has been assayed experimentally. It is a manually curated database where entries are collected & compiled from published literature and existing immunological public databases. MHCBN has a number of web-based tools for the analysis and retrieval of information like mapping of antigenic regions, creation of allele specific dataset, BLAST search, various diseases associated with MHC alleles etc. Further, all entries are hyper linked to major databases like SWISS-PROT, PDB etc. to provide the information beyond the scope of MHCBN. The latest version 4.0 of MHCBN has 6080 more entries than previously published version 1.1.
    CONCLUSION: MHCBN database updating is meant to facilitate immunologist in understanding the immune system and provide them the latest information. We feel that our database will complement the existing databases in serving scientific community.

    BMC Res Notes 2009:2()

    31 Citations (from Europe PMC, 2019-07-13)

  • MHCBN: a comprehensive database of MHC binding and non-binding peptides. [PMID: 12651731]
    Bhasin M, Singh H, Raghava GP.

    MHCBN is a comprehensive database of Major Histocompatibility Complex (MHC) binding and non-binding peptides compiled from published literature and existing databases. The latest version of the database has 19 777 entries including 17 129 MHC binders and 2648 MHC non-binders for more than 400 MHC molecules. The database has sequence and structure data of (a) source proteins of peptides and (b) MHC molecules. MHCBN has a number of web tools that include: (i) mapping of peptide on query sequence; (ii) search on any field; (iii) creation of data sets; and (iv) online data submission. The database also provides hypertext links to major databases like SWISS-PROT, PDB, IMGT/HLA-DB, GenBank and PUBMED.

    Bioinformatics 2003:19(5)

    93 Citations (from Europe PMC, 2019-07-13)

Rank

  • Ranking in all databases: No. 868
  • Ranking in category/categories:
    • Health and medicine: No. 156
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of MHCBN.

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Record metadata

  • Created on: 2019-01-15
    • ***ina@***c.cn [2019-05-29]
    • ***ina@***c.cn [2019-05-24]
    • ***d@***c.cn [2019-01-15]
    • ***d@***c.cn [2019-01-15]

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