PADFrag Edit

Citations: 0

z-index: 0

Basic information
Short name PADFrag
Full name Pesticide And Drug Fragments
Description A Database Built for the Exploration of Bioactive Fragment Space for Drug Discovery.
Year founded
Last update & version
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Central China Normal University
Address Key Laboratory of Pesticide & Chemical Biology of Ministry of Education College of Chemistry, Central China Normal University
City Wuhan
Province/State Hubei
Country/Region China
Contact name (PI/Team) Guang-Fu Yang
Contact email (PI/Helpdesk)
Data information
Data object
Data type
Database category
Major organism
  • PADFrag: A Database Built for the Exploration of Bioactive Fragment Space for Drug Discovery. [PMID: 30134653]
    Jing-Fang Yang, Fan Wang, Wen Jiang, Guang-You Zhou, Cheng-Zhang Li, Xiao-Lei Zhu, Ge-Fei Hao, Guang-Fu Yang

    Structural analyses of drugs and pesticides can enable the identification of new bioactive compounds with novel and diverse scaffolds as well as improve our understanding of the bioactive fragment space. The Pesticide And Drug Fragments (PADFrag) database is a unique bioinformatic-cheminformatic cross-referencing resource that combines detailed bioactive fragment data and potential targets with a strong focus on quantitative, analytic, and molecular-scale information for the exploration of bioactive fragment space for drug discovery ( ). The main applications of PADFrag are the analysis of the privileged structures within known bioactive molecules, ab initio molecule library design, and core fragment discovery for fragment-based drug design. Other potential applications include prediction of fragment interactions and general pharmaceutical research.

    J Chem Inf Model 2018:58(9)

    0 Citations (from Europe PMC, 2019-07-27)


  • Ranking in all databases: No. 0
  • Ranking in category/categories:
    • Structure: No. 0
    • Health and medicine: No. 0
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of PADFrag.

Word cloud

Related Database



Record metadata

  • Created on: 2019-01-04
    • ***ina@*** [2019-01-23]
    • ***d@*** [2019-01-12]
    • ***d@*** [2019-01-12]
    • ***d@*** [2019-01-04]

Community reviews 0 stars (0 reviews)

quality & quantity
organization & presentation
accessibility & reliability
Reviewed by