EVmiRNA Edit

Citations: 1

z-index: 1

Basic information
Short name EVmiRNA
Full name The Extracellular Vesicles miRNA Database
Description a comprehensive database including miRNA expression profiles, miRNA related drug, miRNA regulated pathways, miRNA function, and related publications.
URL http://bioinfo.life.hust.edu.cn/EVmiRNA
Year founded 2018
Last update & version
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Huazhong University of Science and Technology
Address Department of Bioinformatics and Systems Biology. College of Life Science and Technology Huazhong University of Science and Technology, Wuhan 430074 P.R. China
City Wuhan
Province/State Hubei
Country/Region China
Contact name (PI/Team) Anyuan Guo
Contact email (PI/Helpdesk) guoay@hust.edu.cn
Data information
Data object
Data type
Database category
Major organism
Keyword
Publications
  • EVmiRNA: a database of miRNA profiling in extracellular vesicles. [PMID: 30335161]
    Teng Liu, Qiong Zhang, Jiankun Zhang, Chao Li, Ya-Ru Miao, Qian Lei, Qiubai Li, An-Yuan Guo

    Extracellular vesicles (EVs), such as exosomes and microvesicles, acted as cell-to-cell communication vectors and potential biomarkers for diseases. microRNAs (miRNAs) are the most well studied molecules in EVs, thus a comprehensive investigation of miRNA expression profiles in EVs will be helpful to explore their functions and biomarkers. We curated 462 small RNA sequencing samples of EVs from 17 sources/diseases and constructed the EVmiRNA database (http://bioinfo.life.hust.edu.cn/EVmiRNA) to show the miRNA expression profiles. We found >1000 miRNAs expressed in these EVs and detected specific miRNAs for EVs of each source/disease. EVmiRNA provides three functional modules: (i) the miRNA expression profiles and the sample information of EVs from different sources (such as blood, breast milk etc.); (ii) the specifically expressed miRNAs in different EVs that would be helpful for biomarker identification; (iii) the miRNA annotations including the miRNA expression in EVs and TCGA cancer types, miRNA pathway regulations as well as miRNA function and publications. EVmiRNA has a user-friendly web interface with powerful browse and search functions, as well as data downloading. It is the first database focusing on miRNA expression profiles in EVs and will be useful for the research and application community of EV biomarker, miRNA function and liquid biopsy.

    Nucleic Acids Res 2019:47(D1)

    1 Citations (from Europe PMC, 2019-06-08)

Rank

  • Ranking in all databases: No. 3201
  • Ranking in category/categories:
    • Expression: No. 538
    • Pathway: No. 211
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of EVmiRNA.

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Record metadata

  • Created on: 2019-01-04
    • ***d@***c.cn [2019-01-11]
    • ***d@***c.cn [2019-01-11]
    • ***d@***c.cn [2019-01-11]
    • ***d@***c.cn [2019-01-04]

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