Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

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General information

Description: a manually curated resource of cell markers in human and mouse.
Year founded: 2018
Last update:
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Country/Region: China
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Contact information

University/Institution: Harbin Medical University
Address:
City: Harbin
Province/State: Heilongjiang
Country/Region: China
Contact name (PI/Team): Yun Xiao
Contact email (PI/Helpdesk): xiaoyun@ems.hrbmu.edu.cn

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Record metadata

Created on: 2019-01-03
Curated by:
Dong Zou [2019-01-10]
Dong Zou [2019-01-03]

Ranking

All databases:
323/4692 (93.137%)
Literature:
26/299 (91.639%)
323
Total Rank
26
Citations
26
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Publications

30289549
CellMarker: a manually curated resource of cell markers in human and mouse. [PMID: 30289549]
Zhang X, Lan Y, Xu J, Quan F, Zhao E, Deng C, Luo T, Xu L, Liao G, Yan M, Ping Y, Li F, Shi A, Bai J, Zhao T, Li X, Xiao Y.

One of the most fundamental questions in biology is what types of cells form different tissues and organs in a functionally coordinated fashion. Larger-scale single-cell sequencing and biology experiment studies are now rapidly opening up new ways to track this question by revealing substantial cell markers for distinguishing different cell types in tissues. Here, we developed the CellMarker database (http://biocc.hrbmu.edu.cn/CellMarker/ or http://bio-bigdata.hrbmu.edu.cn/CellMarker/), aiming to provide a comprehensive and accurate resource of cell markers for various cell types in tissues of human and mouse. By manually curating over 100 000 published papers, 4124 entries including the cell marker information, tissue type, cell type, cancer information and source, were recorded. At last, 13 605 cell markers of 467 cell types in 158 human tissues/sub-tissues and 9148 cell makers of 389 cell types in 81 mouse tissues/sub-tissues were collected and deposited in CellMarker. CellMarker provides a user-friendly interface for browsing, searching and downloading markers of diverse cell types of different tissues. Furthermore, a summarized marker prevalence in each cell type is graphically and intuitively presented through a vivid statistical graph. We believe that CellMarker is a comprehensive and valuable resource for cell researches in precisely identifying and characterizing cells, especially at the single-cell level.

Nucleic Acids Res. 2019:47(D1) | 26 Citations (from Europe PMC, 2020-09-12)