| URL: | http://tdrtargets.org/ |
| Full name: | Tropical Disease Research |
| Description: | The TDR Targets Database has been designed and developed as an online resource to facilitate the rapid identification and prioritization of molecular targets for drug development,focusing on pathogens responsible for neglected human diseases. |
| Year founded: | 2008 |
| Last update: | 9/19/2011 |
| Version: | v5.0 |
| Accessibility: | |
| Country/Region: | Argentina |
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| University/Institution: | University of San Martin |
| Address: | Instituto de Investigaciones Biotecnológicas, Universidad de San Martín, San Martín, Buenos Aires, Argentina |
| City: | Buenos Aires |
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| Country/Region: | Argentina |
| Contact name (PI/Team): | Fernán Agüero |
| Contact email (PI/Helpdesk): | fernan@unsam.edu.ar |
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Genomic-scale prioritization of drug targets: the TDR Targets database. [PMID: 18927591]
The increasing availability of genomic data for pathogens that cause tropical diseases has created new opportunities for drug discovery and development. However, if the potential of such data is to be fully exploited, the data must be effectively integrated and be easy to interrogate. Here, we discuss the development of the TDR Targets database (http://tdrtargets.org), which encompasses extensive genetic, biochemical and pharmacological data related to tropical disease pathogens, as well as computationally predicted druggability for potential targets and compound desirability information. By allowing the integration and weighting of this information, this database aims to facilitate the identification and prioritization of candidate drug targets for pathogens. |