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a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

ISHAM-ITS reference DNA barcoding database (International Society of Human and Animal Mycology (ISHAM)-ITS reference DNA barcoding database)

General information

Description: ISHAM is a world wide organization that represents all clinical scientists and fundamental researchers with interest in fungal diseases and fungus-like infections. It is an independant society that is non-political and non-discriminatory. It exists solely to encourage and facilitate the study and practice of all aspects of medical and veterinary mycology. The aim of ISHAM is to facilitate on an international basis the exchange of ideas and information and provide assistance pertaining to medical and veterinary mycology.
Year founded: 2015
Last update:
Version:
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Accessible
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Country/Region: Australia
Data type:
DNA
Data object:
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Major organism:
Keywords:

Contact information

University/Institution: University of Sydney
Address: Molecular Medical Mycology Medicine, Westmead Clinical School, The Westmead Institute for Medical Research, University of Sydney, Sydney, Australia
City: Sydney
Province/State:
Country/Region: Australia
Contact name (PI/Team): Wieland Meyer
Contact email (PI/Helpdesk): wieland.meyer@sydney.edu.au

Record metadata

Created on: 2018-01-28
Curated by:
Sidra Younas [2018-04-12]

Ranking

All databases:
484/4549 (89.382%)
Gene genome and annotation:
182/1212 (85.066%)
Health and medicine:
92/917 (90.076%)
Metadata:
38/437 (91.533%)
484
Total Rank
73
Citations
14.6
z-index

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Publications

25802363
International Society of Human and Animal Mycology (ISHAM)-ITS reference DNA barcoding database--the quality controlled standard tool for routine identification of human and animal pathogenic fungi. [PMID: 25802363]
Irinyi L, Serena C, Garcia-Hermoso D, Arabatzis M, Desnos-Ollivier M, Vu D, Cardinali G, Arthur I, Normand AC, Giraldo A, da Cunha KC, Sandoval-Denis M, Hendrickx M, Nishikaku AS, de Azevedo Melo AS, Merseguel KB, Khan A, Parente Rocha JA, Sampaio P, da Silva Briones MR, e Ferreira RC, de Medeiros Muniz M, Castañón-Olivares LR, Estrada-Barcenas D, Cassagne C, Mary C, Duan SY, Kong F, Sun AY, Zeng X, Zhao Z, Gantois N, Botterel F, Robbertse B, Schoch C, Gams W, Ellis D, Halliday C, Chen S, Sorrell TC, Piarroux R, Colombo AL, Pais C, de Hoog S, Zancopé-Oliveira RM, Taylor ML, Toriello C, de Almeida Soares CM, Delhaes L, Stubbe D, Dromer F, Ranque S, Guarro J, Cano-Lira JF, Robert V, Velegraki A, Meyer W.

Human and animal fungal pathogens are a growing threat worldwide leading to emerging infections and creating new risks for established ones. There is a growing need for a rapid and accurate identification of pathogens to enable early diagnosis and targeted antifungal therapy. Morphological and biochemical identification methods are time-consuming and require trained experts. Alternatively, molecular methods, such as DNA barcoding, a powerful and easy tool for rapid monophasic identification, offer a practical approach for species identification and less demanding in terms of taxonomical expertise. However, its wide-spread use is still limited by a lack of quality-controlled reference databases and the evolving recognition and definition of new fungal species/complexes. An international consortium of medical mycology laboratories was formed aiming to establish a quality controlled ITS database under the umbrella of the ISHAM working group on "DNA barcoding of human and animal pathogenic fungi." A new database, containing 2800 ITS sequences representing 421 fungal species, providing the medical community with a freely accessible tool at http://www.isham.org/ and http://its.mycologylab.org/ to rapidly and reliably identify most agents of mycoses, was established. The generated sequences included in the new database were used to evaluate the variation and overall utility of the ITS region for the identification of pathogenic fungi at intra-and interspecies level. The average intraspecies variation ranged from 0 to 2.25%. This highlighted selected pathogenic fungal species, such as the dermatophytes and emerging yeast, for which additional molecular methods/genetic markers are required for their reliable identification from clinical and veterinary specimens.

Med Mycol. 2015:53(4) | 73 Citations (from Europe PMC, 2020-07-11)