Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

Cildb

General information

Description: Cildb is a knowledgebase, built by the Paramecium Lab at Gif-sur-Yvette, dedicated to proteins involved in centrioles, centrosomes, basal bodies, cilia and flagella in eukaryotes.
Year founded: 2009
Last update: 2014
Version: 3.0
Accessibility:
Manual:
Accessible
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Country/Region: France
Data type:
Data object:
NA
Database category:
Major organism:
Keywords:

Contact information

University/Institution: The French National Center for Scientific Research
Address:
City:
Province/State:
Country/Region: France
Contact name (PI/Team): Jean Cohen
Contact email (PI/Helpdesk): cohen@cgm.cnrs-gif.fr

Record metadata

Created on: 2018-01-26
Curated by:
Fatima Batool [2018-12-27]
zhuang xiong [2018-02-22]

Ranking

All databases:
1542/4549 (66.124%)
Structure:
192/615 (68.943%)
Health and medicine:
289/917 (68.593%)
1542
Total Rank
42
Citations
3.818
z-index

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Publications

20428338
Cildb: a knowledgebase for centrosomes and cilia. [PMID: 20428338]
Arnaiz O, Malinowska A, Klotz C, Sperling L, Dadlez M, Koll F, Cohen J.

Ciliopathies, pleiotropic diseases provoked by defects in the structure or function of cilia or flagella, reflect the multiple roles of cilia during development, in stem cells, in somatic organs and germ cells. High throughput studies have revealed several hundred proteins that are involved in the composition, function or biogenesis of cilia. The corresponding genes are potential candidates for orphan ciliopathies. To study ciliary genes, model organisms are used in which particular questions on motility, sensory or developmental functions can be approached by genetics. In the course of high throughput studies of cilia in Paramecium tetraurelia, we were confronted with the problem of comparing our results with those obtained in other model organisms. We therefore developed a novel knowledgebase, Cildb, that integrates ciliary data from heterogeneous sources. Cildb links orthology relationships among 18 species to high throughput ciliary studies, and to OMIM data on human hereditary diseases. The web interface of Cildb comprises three tools, BioMart for complex queries, BLAST for sequence homology searches and GBrowse for browsing the human genome in relation to OMIM information for human diseases. Cildb can be used for interspecies comparisons, building candidate ciliary proteomes in any species, or identifying candidate ciliopathy genes.Database URL:http://cildb.cgm.cnrs-gif.fr.

Database (Oxford). 2009:2009() | 42 Citations (from Europe PMC, 2020-02-08)