Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database information

LncRNA2Target (LncRNA-target association database)

General information

Description: LncRNA2Target is a database for differentially expressed genes after lncRNA knockdown or overexpression.
Year founded: 2014
Last update: 2014-08-02
Version: v1.2
Accessibility:
Manual:
Accessible
Real time : Checking...
Country/Region: China
Data type:
RNA
Data object:
Database category:
Major organism:
Keywords:

Contact information

University/Institution: Harbin Institute of Technology
Address: Harbin,Heilongjiang 150001,China
City: Harbin
Province/State: Heilongjiang
Country/Region: China
Contact name (PI/Team): Yadong Wang
Contact email (PI/Helpdesk): ydwang@hit.edu.cn

Record metadata

Created on: 2015-06-20
Curated by:
Dong Zou [2019-01-04]
Dong Zou [2018-03-05]
Chunlei Yu [2016-04-17]
Chunlei Yu [2016-04-01]
Mengwei Li [2016-02-18]
Lina Ma [2015-11-18]
Chunlei Yu [2015-06-29]

Ranking

All databases:
476/4549 (89.558%)
Expression:
68/800 (91.625%)
Modification:
20/185 (89.73%)
476
Total Rank
74
Citations
14.8
z-index

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Publications

30380072
LncRNA2Target v2.0: a comprehensive database for target genes of lncRNAs in human and mouse. [PMID: 30380072]
Cheng L, Wang P, Tian R, Wang S, Guo Q, Luo M, Zhou W, Liu G, Jiang H, Jiang Q.

Long non-coding RNAs (lncRNAs) play crucial roles in regulating gene expression, and a growing number of researchers have focused on the identification of target genes of lncRNAs. However, no online repository is available to collect the information on target genes regulated by lncRNAs. To make it convenient for researchers to know what genes are regulated by a lncRNA of interest, we developed a database named lncRNA2Target to provide a comprehensive resource of lncRNA target genes in 2015. To update the database this year, we retrieved all new lncRNA-target relationships from papers published from 1 August 2014 to 30 April 2018 and RNA-seq datasets before and after knockdown or overexpression of a specific lncRNA. LncRNA2Target database v2.0 provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene, and is freely accessible at http://123.59.132.21/lncrna2target.

Nucleic Acids Res. 2019:47(D1) | 29 Citations (from Europe PMC, 2020-02-08)
25399422
LncRNA2Target: a database for differentially expressed genes after lncRNA knockdown or overexpression. [PMID: 25399422]
Jiang Q, Wang J, Wu X, Ma R, Zhang T, Jin S, Han Z, Tan R, Peng J, Liu G, Li Y, Wang Y.

Long non-coding RNAs (lncRNAs) have emerged as critical regulators of genes at epigenetic, transcriptional and post-transcriptional levels, yet what genes are regulated by a specific lncRNA remains to be characterized. To assess the effects of the lncRNA on gene expression, an increasing number of researchers profiled the genome-wide or individual gene expression level change after knocking down or overexpressing the lncRNA. Herein, we describe a curated database named LncRNA2Target, which stores lncRNA-to-target genes and is publicly accessible at http://www.lncrna2target.org. A gene was considered as a target of a lncRNA if it is differentially expressed after the lncRNA knockdown or overexpression. LncRNA2Target provides a web interface through which its users can search for the targets of a particular lncRNA or for the lncRNAs that target a particular gene. Both search types are performed either by browsing a provided catalog of lncRNA names or by inserting lncRNA/target gene IDs/names in a search box. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

Nucleic Acids Res. 2015:43(Database issue) | 45 Citations (from Europe PMC, 2020-02-15)