PceRBase Edit

Citations: 4

z-index: 4

Basic information
Short name PceRBase
Full name Plant ceRNA database
Description PceRBase contains potential ceRNA target-target, and ceRNA target-mimic pairs from 26 plant species.
URL http://bis.zju.edu.cn/pcernadb/index.jsp
Year founded 2015
Last update & version 2016-06-28
Availability Free to all users
Contact information
University/Institution hosted Zhejiang University
Address College of Life Sciences
City Hangzhou
Province/State Zhejiang
Country/Region China
Contact name Ming Chen
Contact email mchen@zju.edu.cn
Data information
Object(s)
Data type(s)
  • RNA
Data Category/Categories
Major organism(s)
Keyword(s)
  • competing endogenous RNA (ceRNA)
  • long non-coding RNA
  • miRNA
Publications
  • PceRBase: a database of plant competing endogenous RNA.[PMID: 28053167]
    Chunhui Yuan, Xianwen Meng, Xue Li, Nicola Illing, Robert A Ingle, Jingjing Wang, Ming Chen

    Competition for microRNA (miRNA) binding between RNA molecules has emerged as a novel mechanism for the regulation of eukaryotic gene expression. Competing endogenous RNA (ceRNA) can act as decoys for miRNA binding, thereby forming a ceRNA network by regulating the abundance of other RNA transcripts which share the same or similar microRNA response elements. Although this type of RNA cross talk was first described in Arabidopsis, and was subsequently shown to be active in animal models, there is no database collecting potential ceRNA data for plants. We have developed a Plant ceRNA database (PceRBase, http://bis.zju.edu.cn/pcernadb/index.jsp) which contains potential ceRNA target-target, and ceRNA target-mimic pairs from 26 plant species. For example, in Arabidopsis lyrata, 311 candidate ceRNAs are identified which could affect 2646 target-miRNA-target interactions. Predicted pairing structure between miRNAs and their target mRNA transcripts, expression levels of ceRNA pairs and associated GO annotations are also stored in the database. A web interface provides convenient browsing and searching for specific genes of interest. Tools are available for the visualization and enrichment analysis of genes in the ceRNA networks. Moreover, users can use PceRBase to predict novel competing mimic-target and target-target interactions from their own data. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

    Nucleic acids research 2017:45(D1)

    4 Citations (from Europe PMC, 2018-10-12)

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Record metadata

  • Created on: 2017-02-21
    • Ma Lina [2017-06-14]
    • Sun Shixiang [2017-02-20]

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