RBCC Edit

Citations: 6

z-index: 1.5

Basic information
Short name RBCC
Full name Red Blood Cell Collection
Description RBCC provides a significant set of possible membrane protein biomarkers in red blood cell membrane.
URL http://rbcc.hegelab.org
Year founded 2013
Last update & version 2015-01-01 v1.0
Accessibility Accessible
Contact information

The contact information is provided to facilitate update of database information, and it is curated based on the contact details in the database or the related publications. To ensure effective contact with database constructors, we give priority to the contact details in the database.

University/Institution Institute of Enzymology, Hungarian Academy of Sciences
Address 37-47, H-1094 Budapest, Hungary
City Budapest
Province/State
Country/Region Hungary
Contact name (PI/Team) Tamás Hegedűs
Contact email (PI/Helpdesk) hegedus@hegelab.org
Data information
Data object
Data type
Database category
Major organism
Keyword
Publications
  • Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications. [PMID: 26078478]
    Tamás Heged?s, Pururawa Mayank Chaubey, György Várady, Edit Szabó, Hajnalka Sarankó, Lia Hofstetter, Bernd Roschitzki, Bruno Stieger, Balázs Sarkadi

    Based on recent results, the determination of the easily accessible red blood cell (RBC) membrane proteins may provide new diagnostic possibilities for assessing mutations, polymorphisms or regulatory alterations in diseases. However, the analysis of the current mass spectrometry-based proteomics datasets and other major databases indicates inconsistencies-the results show large scattering and only a limited overlap for the identified RBC membrane proteins. Here, we applied membrane-specific proteomics studies in human RBC, compared these results with the data in the literature, and generated a comprehensive and expandable database using all available data sources. The integrated web database now refers to proteomic, genetic and medical databases as well, and contains an unexpected large number of validated membrane proteins previously thought to be specific for other tissues and/or related to major human diseases. Since the determination of protein expression in RBC provides a method to indicate pathological alterations, our database should facilitate the development of RBC membrane biomarker platforms and provide a unique resource to aid related further research and diagnostics. © The Author(s) 2015. Published by Oxford University Press.

    Database (Oxford) 2015:2015()

    6 Citations (from Europe PMC, 2019-06-22)

Rank

  • Ranking in all databases: No. 2641
  • Ranking in category/categories:
    • Gene genome and annotation: No. 786
    • Expression: No. 481
The box plots depict Z-index distribution for all databases in Database Commons and for specific database category/categories. The red line indicates log2(Z-index) of RBCC.

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Record metadata

  • Created on: 2016-01-15
    • ***ina@***c.cn [2019-06-10]
    • ***lin@***c.cn [2016-04-01]
    • ***lin@***c.cn [2016-01-27]

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