Database Commons

a catalog of biological databases

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Database information

Kinomer

General information

Description: Kinomer is a database of systematically classified eukaryotic protein kinases.
Year founded: 2008
Last update: 2008-10-30
Version: v1.0
Accessibility:
Manual:
Accessible
Real time : Checking...
Country/Region: United Kingdom
Data type:
Data object:
NA
Database category:
Major organism:
NA
Keywords:

Contact information

University/Institution: University of Dundee
Address: Dow Street, Dundee DD1 5EH, Scotland, UK
City: Dundee
Province/State:
Country/Region: United Kingdom
Contact name (PI/Team): Geoffrey J. Barton
Contact email (PI/Helpdesk): gjbarton@dundee.ac.uk

Record metadata

Created on: 2015-07-21
Curated by:
[2018-11-28]
Lina Ma [2018-06-13]
Chunlei Yu [2016-03-31]
Zhang Zhang [2016-02-06]
Chunlei Yu [2015-11-20]

Ranking

All databases:
1521/4549 (66.586%)
Gene genome and annotation:
474/1211 (60.941%)
1521
Total Rank
43
Citations
3.909
z-index

Community reviews

Not Rated
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Word cloud

Publications

18974176
Kinomer v. 1.0: a database of systematically classified eukaryotic protein kinases. [PMID: 18974176]
Martin DM, Miranda-Saavedra D, Barton GJ.

The regulation of protein function through reversible phosphorylation by protein kinases and phosphatases is a general mechanism controlling virtually every cellular activity. Eukaryotic protein kinases can be classified into distinct, well-characterized groups based on amino acid sequence similarity and function. We recently reported a highly sensitive and accurate hidden Markov model-based method for the automatic detection and classification of protein kinases into these specific groups. The Kinomer v. 1.0 database presented here contains annotated classifications for the protein kinase complements of 43 eukaryotic genomes. These span the taxonomic range and include fungi (16 species), plants (6), diatoms (1), amoebas (2), protists (1) and animals (17). The kinomes are stored in a relational database and are accessible through a web interface on the basis of species, kinase group or a combination of both. In addition, the Kinomer v. 1.0 HMM library is made available for users to perform classification on arbitrary sequences. The Kinomer v. 1.0 database is a continually updated resource where direct comparison of kinase sequences across kinase groups and across species can give insights into kinase function and evolution. Kinomer v. 1.0 is available at http://www.compbio.dundee.ac.uk/kinomer/.

Nucleic Acids Res. 2009:37(Database issue) | 43 Citations (from Europe PMC, 2020-02-15)