Accession SAMC016542
Sample name MDA-MB-231 breast non cancer stem cells
Title MDA-MB-231 breast non cancer stem cells
Sample type Human sample
Organisms Homo sapiens
Description Cancer stem cells (CSCs) refer to a group of stem cell like cells in tumor. However, how CSCs maintain their self-renewal, high invasion and radio/chemo-therapy resistance capacities is still unclear. In this study, we compared CSCs and non-CSCs with respect to transcriptome, DNA methylome and the distribution of two histone modifications, H3K4me2 and H3K27me3, the latter two used as proxies for active and inactive chromatin, respectively, to investigate this mechanism.
Attributes
Isolate NCSCs were identified and separated by CD44+/CD24+, CD44-/CD24- or CD44-/CD24+.
Age
Biomaterial provider ATCC: The Global Bioresource Center
Sex female
Tissue breast cancer cell line
Disease breast cancer
Cell line
Cell subtype
Cell type
Culture collection
Development stage
Disease stage
Ethnicity
Health State
Karyotype
Phenotype
Population
Race
Type
Treatment
Release Date 2019-09-04
Accession PRJCA000539
Submitter Guochao  Li  (liguochao@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission Date 2017-09-04

Sample Data

Resource Name Description
GSA (1) -
CRA000465 RNA-seq, WGBS and ChIP-seq (H3K4me2 and H3K27me3) of triple negative breast cancer stem cells and non-cancer stem cells
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Related Samples
Samples (1)