Accession PRJCA003492
Title Discovery of a degrader for AML differentiation therapy
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description We have we set different experimental groups with different time points to conduct RNA-seq analysis, including control group, shCDK2 #1 and #2 (D2.5, D3, D4 and D5), CPS2 group (12h, D1, D2, D3), as well as J2 (12h, D1, D2, D3) to test the difference of inducing differentiation efficacy.
Sample scope Monoisolate
Release date 2020-09-18
Publication
PubMed ID Article title Journal name DOI Year
33664520 Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy Nature Chemical Biology 10.1038/s41589-021-00742-5 2021
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81573277
National Natural Science Foundation of China (NSFC) 81622042
National Natural Science Foundation of China (NSFC) 81773567
Submitter Liguo    Wang  (wangl.g@foxmail.com)
Organization Tsinghua University
Submission date 2020-09-18

Project Data

Resource name Description
BioSample (16)  show -
GSA (1) -
CRA003240 Discovery of a degrader for AML differentiation therapy