Accession PRJCA003151
Title gut microbiome in VKH disease
Relevance Medical
Data types Metagenome
Organisms human gut metagenome
Description Vogt-Koyanagi-Harada (VKH) disease is a multisystemic autoimmune disorder characterized by granulomatous panuveitis but whether the alternation of gut microbiome was involved is unclear. This study was set up to identify abnormalities of gut microbiome composition in VKH disease. Our results revealed a distinct gut microbiome signature in VKH patients and showed an exacerbating effect of this gut microbiome on experimental autoimmune uveitis (EAU). We also developed two microbial marker profiles in differentiating VKH patients from healthy controls as well as predicting the effectiveness of treatment.
Sample scope faeces
Release date 2020-08-05
Publication
PubMed ID Article title Journal name DOI Year
31928124 Altered gut microbiome composition in patients with Vogt-Koyanagi-Harada disease Gut Microbes 10.1080/19490976.2019.1700754 2020
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2016YFC0904000
National Natural Science Foundation of China (NSFC) International (Regional) Joint Research Programs 81720108009
Accessions in other database
Accession Database name
PRJNA356225 NCBI
Submitter Peizeng    Yang  (peizengycmu@126.com)
Organization The First Affiliated Hospital of Chongqing Medical University
Submission date 2020-07-30

Project Data

Resource name Description
BioSample (118)  show -
GSA (1) -
CRA003045 gut microbiome in VKH disease