Accession PRJCA002591
Title Single cell transcriptome analysis reveals six subpopulations reflecting distinct cellular fates in senescent mouse embryonic fibroblasts
Relevance Medical
Data types Transcriptome or Gene expression
Raw sequence reads
Organisms Mus musculus
Description we conducted single cell RNA sequencing on senescent MEFs. PCA analyses showed there were obvious heterogeneity among these MEFs and they could be divided into six subpopulations. Three lines of gene expression analyses indicated distinct expression features of these six subpopulations.
Sample scope Single cell
Release date 2020-04-24
Publication
PubMed ID Article title Journal name DOI Year
32849838 Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts Frontiers in Genetics 10.3389/fgene.2020.00867 2020
Grants
Agency program Grant ID Grant title
National Key R&D Program of China 2018YFC1003500
National Natural Science Foundation of China (NSFC) 31771336
National Natural Science Foundation of China (NSFC) 31521003
National Natural Science Foundation of China (NSFC) 91949107
Submitter wei    chen  (1006891674@qq.com)
Organization Fudan University
Submission date 2020-04-24

Project Data

Resource name Description
BioSample (175)  show -
GSA (1) -
CRA002582 Single cell transcriptome analysis reveals six subpopulations reflecting distinct cellular fates in senescent mouse embryonic fibroblasts