| Accession |
PRJCA002531 |
| Title |
Single-cell profiling reveals pathogenic pathways and therapeutic targets for infant biliary atresia |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
Biliary Atresia is a severe cholangiopathy mediated by extrahepatic bile duct obstruction, causing pathological jaundice and liver failure in early infancy. Using single-cell RNA sequencing, we revealed immune pathogenic pathways that promote liver failure in infants. |
| Sample scope |
Single cell |
| Release date |
2020-11-28 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33248023
|
Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia
|
Cell
|
10.1016/j.cell.2020.10.048
|
2020
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
91742109
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
31770978
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81971430
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81771629
|
|
| National Natural Science Foundation of China (NSFC)
|
Major Program
|
2018ZX10302205
|
|
| National Natural Science Foundation of China (NSFC)
|
Major Program
|
2019YFC1315702
|
|
|
|
| Submitter |
Yuxia
Zhang (yuxia.zhang@gwcmc.org)
|
| Organization |
Guangzhou Women and Children's Medical Center |
| Submission date |
2020-04-14 |
