Accession | PRJCA002445 | ||||||||||||||||
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Title | Molecular Parallelisms and Divergences Between Human and Dog Cancers | ||||||||||||||||
Relevance | Medical | ||||||||||||||||
Umbrella project |
eGPS: evolutionary Genotype-Phenotype Systems biology Key theories & Model High performance integration analysis of large data of biological groups |
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Data types |
Whole genome sequencing
Raw sequence reads |
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Organisms | Canis lupus familiaris | ||||||||||||||||
Description | Evolutionary theories are critical for understanding tumorigenesis at the level of species as well as at the level of cells and tissues, for the development of effective therapies. Cross-species cancer genomics, independent evolution of cancer from normal tissues, provide an excellent opportunity to address an evolutionary perspective of cancer. The dog really can be an appropriate experimental model for human cancers from the genomic and evolutionary perspective or not. Canine mammary carcinoma shows a diversity of histological types of mammary tumor compares to Human breast cancer. | ||||||||||||||||
Sample scope | Multiisolate | ||||||||||||||||
Release date | 2020-04-01 | ||||||||||||||||
Grants |
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Submitter | Sadaf Ambreen (sdf.ambreen@gmail.com) | ||||||||||||||||
Organization | Beijing Institute of Genomics, Chinese Academy of Sciences | ||||||||||||||||
Submission date | 2020-03-26 |