Accession |
PRJCA002408 |
Title |
Mapping the spreading routes of lymphatic metastases in human colorectal cancer |
Relevance |
Medical |
Data types |
Exome
|
Organisms |
Homo sapiens
|
Description |
Lymph node metastases are frequently diagnosed in patients with colorectal cancer. However, the detailed disseminating routes of cancer cells within the lymphatic network remain largely unknown. Here, we analyzed the subclonal structure of 94 tumor samples from 10 CRC patients, covering almost all LNMs, as well as primary tumor and liver metastases. We portrayed the first lymphatic metastatic map for CRC. |
Sample scope |
Multiisolate |
Release date |
2020-03-19 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
32332722
|
Mapping the spreading routes of lymphatic metastases in human colorectal cancer
|
Nature Communications
|
10.1038/s41467-020-15886-6
|
2020
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
Chinese Academy of Medical Sciences (CAMS)
|
|
201612M1007
|
|
National Natural Science Foundation of China (NSFC)
|
|
81272769
|
|
National Science and Technology Major Project
|
|
2018ZX10302205
|
|
Guangdong Province Key Research and Development Program
|
|
2019B020226002
|
|
National Natural Science Foundation of China (NSFC)
|
|
81802813
|
|
|
Submitter |
Fan
Bai (fbai@pku.edu.cn)
|
Organization |
Peking University |
Submission date |
2020-03-19 |