Accession PRJCA002164
Title Global Immune Characterization of Hepatocellular Carcinoma Identifies Macrophage and T cell Subsets Associated with Disease Progression
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Homo sapiens
Description Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular carcinoma (HCC) remains poorly understood. We assess the variability and phenotypes of immune cells within HCC microenvironment by performing single-cell RNA sequencing on 41,698 immune cells from 7 pairs of HCC tumors and nontumor liver tissues.
Sample scope Single cell
Release date 2020-01-25
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 91859105
National Natural Science Foundation of China (NSFC) 81961128025
Basic Research Project from Technology Commission of Shanghai Municipality 17JC1402200
Submitter song  guo  he  (docsong2013@163.com)
Organization Fudan University
Submission date 2020-01-25

Project Data

Resource name Description
BioSample (14)  show -
GSA (1) -
CRA002308 Global Immune Characterization of Hepatocellular Carcinoma Identifies Macrophage and T cell Subsets Associated with Disease Progression