Accession PRJCA001698
Title Landscape and dynamics of single immune cells in hepatocellular carcinoma
Relevance Model organism
Data types Raw sequence reads
Organisms Homo sapiens
Description Combining 3 prime and full-length single-cell RNA sequencing technologies, we produced profile of 77,321 CD45+ immune cells for HCC patients from five immune-relevant sites: tumor, adjacent liver, hepatic lymph node (LN), blood, and ascites. Our study not only characterizes the immune composition of HCC but also provides the dynamics of tumor-infiltrating immune cells across tissues, shedding new lights to the immune landscape of HCC.
Sample scope Single cell
Release date 2019-11-05
Publication
PubMed ID Article title Journal name DOI Year
31675496 Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma Cell 10.1016/j.cell.2019.10.003 2019
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 31530036
National Natural Science Foundation of China (NSFC) 91742203
Beijing Advanced Innovation Centre for Genomics at Peking University Key Technologies R&D Program 2016YFC0900100
Submitter Zemin    Zhang  (zemin@pku.edu.cn)
Organization Peking University
Submission date 2019-08-26

Project Data

Resource name Description