| Accession |
PRJCA001540 |
| Title |
Landscape of tumor-infiltrating immune cells in colorectal cancer |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
Raw sequence reads
|
| Organisms |
|
| Description |
We utilized two scRNA-seq platforms (Smart-seq2 and 10x) to perform a comprehensive, high resolution analysis of immune and stromal cell populations in tumor, normal tissue, and blood from 18 treatment-naive CRC patients to provide novel insights into the heterogeneity and function of these cells, their role in shaping the TME, and the translatability of myeloid modulating therapies from pre-clinical models to human cancer. |
| Sample scope |
Single cell |
| Release date |
2019-06-27 |
| Biomaterial provider |
Department of Gastroenterological Surgery, Peking University People Hospital |
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81573022
|
|
| National Natural Science Foundation of China (NSFC)
|
|
31530036
|
|
| National Natural Science Foundation of China (NSFC)
|
|
91742203
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81672375
|
|
| Beijing Advanced Innovation Center for Genomics at Peking University, Key Technologies R&D Program
|
|
2016YFC0900100
|
|
|
|
| External link |
| External link |
Link description |
| http://cancer-pku.cn:3838/CRC_Leukocyte/ |
An interactive, web-based tool for analyzing, visualizing, and downloading our single-cell data for single or multiple user-input genes. |
|
|
| Submitter |
ZIyi
Li (liziyie@pku.edu.cn)
|
| Organization |
Peking University |
| Submission date |
2019-06-27 |
