Accession PRJCA001532
Title Intestinal Microbiome in Children with Autism Spectrum Disorder
Relevance Medical
Data types Metagenome
Raw sequence reads
Organisms Bacteria
Description Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder, whose incidence is mounting worldwide. There is growing awareness that ASD is highly associated with dysbiosis in gut microbiome. However, the altered pattern of gut microbiome is not consistent across studies and how the microbiome affects ASD is largely unknown. Therefore, we conducted a metagenomic analysis for the intestinal microbiome of 39 ASD children and 40 typical developmental heathy controls (HC) to explore their difference in metabolic functions and microbiome-related pathogenic mechanisms.
Sample scope Environment
Release date 2020-10-27
Publication
PubMed ID Article title Journal name DOI Year
33087359 A quasi-paired cohort strategy reveals the impaired detoxifying function of microbes in the gut of autistic children Science Advances 10.1126/sciadv.aba3760 2020
Biomaterial provider Autism research center of Peking University Health Science Center
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) General Program 31671350
Peking University Medical Sciences Center BJMU88443Y0306
Peking University Medical Sciences Center BMU2018MX002
Submitter Yanan    Chu  (chuyn@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission date 2019-06-25

Project Data

Resource name Description
BioSample (79)  show -
GSA (1) -
CRA001746 ASD-gut