Accession PRJCA001417
Title Whole exome sequencing to identify novel mutations in sporadic odontogenic keratocysts
Relevance Medical
Data Types Exome
Organisms Homo sapiens
Description Odontogenic keratocysts (OKCs) are benign jaw lesions with high growth potential and propensity for recurrence. Our previous study revealed that PTCH1 mutations, which were frequently detected in sporadic OKCs, might be underestimated due to the masking effect of the stromal components within the tested tissues. We aimed to confirm these results in larger scale and further present the unbiased view of the genomic basis of sporadic OKCs except PTCH1.
Sample scope Multiisolate
Release date 2019-05-07
PubMed ID Article title Journal name DOI Year
31162759 PTCH1 alterations are frequent but other genetic alterations are rare in sporadic odontogenic keratocysts Oral Diseases 10.1111/odi.13135 2019
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81671006
National Natural Science Foundation of China (NSFC) 81030018
Beijing Nature Science Foundation 7172238
Submitter Jiafei    Qu  (
Organization Peking University School and Hospital of Stomatology
Submission date 2019-05-07

Project Data

Resource name Description
BioSample (10) -
SAMC069959 OKC-38-control
SAMC069958 OKC-37-control
SAMC069957 OKC-36-control
SAMC069956 OKC-19-control
SAMC069955 OKC-18-control
SAMC069447 OKC-38
SAMC069446 OKC-37
SAMC069445 OKC-36
SAMC069444 OKC-19
SAMC069443 OKC-18
GSA (1) -
CRA001584 whole exome sequencing data of sporadic OKCs