Accession |
PRJCA001414 |
Title |
ADNP maintains pluripotent stem cells by inhibiting primitive endoderm differentiation |
Relevance |
Stem cells |
Data types |
Transcriptome or Gene expression
Raw sequence reads
ATAC-Sequence, ChIP-Sequence, RNA-Sequence
|
Organisms |
Mus
|
Description |
Our work revealed that ADNP is required for ES cell self-renewal and pluripotency by repressing endoderm-specific lineage genes through maintaining chromatin configuration via association with BRG1 and CHD4. |
Sample scope |
Multiisolate |
Release date |
2019-12-21 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
32533114
|
ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling
|
Nature Communications
|
10.1038/s41467-020-16799-0
|
2020
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key R&D Program
|
2016YFA0101100
|
Construction of Heart Valve Based on Autologous Stem Cells
|
National Natural Science Foundation of China (NSFC)
|
General Program
|
Y713091501
|
MGA regulates BMP signal transduction and Chromatin remodeling
|
Chinese Academy of Sciences (CAS)
|
Program of Chinese Academy of Sciences (CAS)
|
Y623041501
|
Research fund of one hundred talents of Chinese Academy of Sciences (CAS)
|
|
Submitter |
Sun
Xiaoyun (sunnyxyun@163.com)
|
Organization |
Institute of Hydrobiology, Chinese Academy of Sciences |
Submission date |
2019-05-06 |