Accession PRJCA001403
Title Genome-wide analysis of DNA methylation profiles identified several tumor suppressor genes in laryngeal squamous cell carcinoma
Relevance Medical
Data types Whole genome sequencing
Raw sequence reads
Genome sequencing
Organisms Homo sapiens
Description DNA methylation is one of the most important epigenetic mechanisms in regulating gene expression. Laryngeal squamous cell carcinoma is one of the most common head and neck carcinomas with high mortality rate. The molecular mechanisms of LSCC need to be extensively explored. In the present study, Whole genome bisulfite Sequencing method was applied to compare DNA methylomes of laryngeal squamous cell carcinoma tissues and the adjacent non-cancerous normal tissues and identify the differentially methylated regions (DMRs).
Sample scope Multiisolate
Release date 2019-04-29
Agency program Grant ID Grant title
Natural Science Foundation of Fujian Province 2016J01548
Professor Foundation of Fujian Medical University JS15019
Medical Innovation Project of Fujian Medical University 2017CX23
Industry-University-Research Collaboration Project of Fujian Province Educational Department JAT160187
Submitter Desheng    Wang  (
Organization Fujian Medical University Union Hospital
Submission date 2019-04-29

Project Data

Resource name Description
BioSample (2) -
SAMC068548 Pooled laryngeal squamous cell carcinoma sample
SAMC072550 Pooled adjacent non-cancerous normal sample
GSA (1) -
CRA001566 Whole genome bisulfite sequencing data of laryngeal cancer