| Accession | PRJCA001393 | ||||||||||||||||||||||||||||||||||||||||||||
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| Title | A Single-Cell RNA Sequencing Profiles the Developmental Landscape of Arabidopsis Root | ||||||||||||||||||||||||||||||||||||||||||||
| Relevance | Agricultural | ||||||||||||||||||||||||||||||||||||||||||||
| Data types | Transcriptome or Gene expression | ||||||||||||||||||||||||||||||||||||||||||||
| Organisms | Arabidopsis thaliana | ||||||||||||||||||||||||||||||||||||||||||||
| Description | Cells have the inherent heterogeneity. Recent advances in the single-cell gene expression studies enable us to explore transcriptional regulation in dynamic development processes and highly heterogeneous cell populations. Using high-throughput single-cell RNA sequencing (scRNA-seq) assay, we found that the cells in Arabidopsis root are highly heterogeneous in their transcriptomes. A total of 24 putative cell clusters and their cluster-specific marker genes were identified. The spatial distribution and temporal ordering of the individual cell at different developmental stages illustrate their hierarchical structure and reconstructs continuous differentiation trajectory of root development. Moreover, we found that each root cell cluster exhibits distinct patterns in ion assimilation and hormone response. Our study thus reveals high degree of heterogeneity of root cells and identifies the expression signatures of intermediate states during root cell differentiation at the single-cell resolution. We have implemented a supplementary web server (http://wanglab.sippe.ac.cn/rootatlas/) to facilitate the use of the datasets generated in this study. | ||||||||||||||||||||||||||||||||||||||||||||
| Sample scope | Single cell | ||||||||||||||||||||||||||||||||||||||||||||
| Release date | 2024-04-11 | ||||||||||||||||||||||||||||||||||||||||||||
| Publication |
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| Grants |
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| Submitter | Zhougeng Xu (xuzhougeng@163.com) | ||||||||||||||||||||||||||||||||||||||||||||
| Organization | Institute of Plant Physiology & Ecology, Chinese Academy of Sciences | ||||||||||||||||||||||||||||||||||||||||||||
| Submission date | 2019-04-26 |
| Resource name | Description |
|---|---|
| BioSample (1) | - |
| SAMC068470 | Root Single-Cell RNA Sequencing |
| GSA (1) | - |
| CRA001559 | scRNA-seq-of-arabidopsis-root |