Accession PRJCA001091
Title MSCs-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer
Relevance Medical
Data Types Raw sequence reads
Organisms Homo sapiens
Description we provide evidence that MSCs promote stemness and chemoresistance in GC cells through FAO. Mechanically, transforming growth factor β1 (TGF-β1) secretion by MSCs induced lncRNA MACC1-AS1 expression in GC cells, which promoted FAO-dependent stemness and chemoresistance through miR-145-5p.
Sample scope Monoisolate
Release date 2019-03-01
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81472317
Submitter Wanming    He  (958116727@qq.com)
Organization Southern Medical University
Submission date 2018-10-22

Project Data

Resource name Description
BioSample (6) -
SAMC047597 Vector_3
SAMC047596 Vector_2
SAMC047595 Vector_1
SAMC047594 MAS1_3
SAMC047593 MAS1_2
SAMC047592 MAS1_1
GSA (1) -
CRA001195 RNA sequence of lncRNA MACC1-AS1
-