Accession PRJCA001076
Title Transcriptomic insight into terpenoid biosynthesis and functional characterization of three diterpene synthases in Scutellaria barbata
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Scutellaria barbata
Description Scutellaria barbata (Lamiaceae) is an important medicinal herb widely used in China, Korea, India, and other Asian countries. Neo-clerodane diterpenoids are the largest known group of Scutellaria diterpenoids and show promising cytotoxic activity against several cancer cell lines. However, little is known about diterpenoid biosynthetic pathways in Scutellaria species. Here, Illumina-based deep transcriptome analysis of flowers, the aerial parts (leaf and stem), and roots of S. barbata was used to explore terpenoid-related genes. In total, 121,958,564 clean RNA-seq reads were assembled into 88,980 transcripts, with an average length of 1,370 nt and N50 length of 2,144 nt, indicating high assembly quality.
Sample scope Monoisolate
Release date 2020-10-16
Publication
PubMed ID Article title Journal name DOI Year
30424547 Transcriptomic Insight into Terpenoid Biosynthesis and Functional Characterization of Three Diterpene Synthases in Scutellaria barbata Molecules 10.3390/molecules23112952 2018
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) 2060302 The ability establishment of sustainable use for valuable Chinese medicine resources.
Submitter Tong    Chen  (chentong_biology@163.com)
Organization National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Submission date 2018-10-16

Project Data

Resource name Description
BioSample (6)  show -
GSA (1) -
CRA001174 Transcriptomic insight into terpenoid biosynthesis and functional characterization of three diterpene synthases in Scutellaria barbata