| Accession |
PRJCA001069 |
| Title |
gene expression in adipose tissues of pig |
| Relevance |
Model organism |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Sus scrofa
|
| Description |
We cultured the lean pig breed Danish-Landrace and the obese breed Min pig to characterize the developmental process of adipose tissues at the juvenile and the juvenile-to-adult stages. Using RNA-seq experiment, we isolated subcutaneous adipose tissues derived from 4-week pigs and 16-week pigs and identified 24,718 of expressed transcription unites. Of which, 6,327 genes were differentially expressed between breeds and/or between developmental stages. Compared with the obese pigs, the up-regulated genes in the lean pig breeds showed significantly function and pathway enrichment in fatty acid degradation and mitochondrial functions. Further analysis uncovered the distinct usage preferences of the three PPARγ alternative promoters associated with the developmental process of adipose tissues in the two breeds. |
| Sample scope |
Multiisolate |
| Release date |
2018-12-05 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 30563100
|
Distinct Patterns of PPARγ Promoter Usage, Lipid Degradation Activity, and Gene Expression in Subcutaneous Adipose Tissue of Lean and Obese Swine
|
International Journal of Molecular Sciences
|
10.3390/ijms19123892
|
2018
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of Heilongjiang Province of China
|
|
QC2017014
|
|
|
|
| Submitter |
Na
Chen (chennvnv@163.com)
|
| Organization |
Institute of Crop Sciences, Chinese Academy of Agricultural Sciences |
| Submission date |
2018-10-13 |
