Accession PRJCA001058
Title RNA m5C methylation enhances rice adaptation to high-temperature stress
Relevance Agricultural
Data types Transcriptome or Gene expression
Raw sequence reads
Organisms Oryza sativa
Description Here, we attempted to address how m5C modification specifically regulates heat stress response in the model monocot plant rice. Our results demonstrate that OsNSUN2 is the mRNA m5C methyltransferase in rice, and the osnsun2 mutants are supersensitive to heat stress. The transcriptome-wide mRNA m5C modification is suppressed by heat stress. By contrast, mRNA m5C modifications in photosynthesis and stress response related genes are selectively induced in an OsNSUN2-dependent manner under heat stress. The heat responsive m5C modification is essential for plant to recover from non-lethal high temperature conditions.
Sample scope Monoisolate
Release date 2020-03-06
Publication
PubMed ID Article title Journal name DOI Year
32275888 OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature Developmental Cell 10.1016/j.devcel.2020.03.009 2020
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 31788103
Chinese Academy of Sciences (CAS) QYZDYSSWSMC027
Submitter Ying    Yang  (yingyang@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission date 2018-10-08

Project Data

Resource name Description
BioSample (24)  show -
GSA (1) -
CRA001149 OsNSUN2-mediated 5-methylcytidine mRNA modification enhances rice adaptation to high-temperature