Accession PRJCA001042
Title Single-cell sequencing of holo-transcriptome
Data Types Exome
Transcriptome or Gene expression
Raw sequence reads
Organisms Mus musculus
Homo sapiens
Description We introduce a single-cell holo-transcriptome sequencing (Holo-Seq) has the same quantitative accuracy and uniform coverage with a complete strand of origin information as bulk RNA-seq. Most importantly, Holo-Seq can simultaneously observe small-RNAs and mRNAs in a single cell. Furthermore, we acquire small-RNA and mRNA dual transcriptomes of 32 human hepatocellular carcinoma single cells, which display the genome-wide super-enhancer activity and hepatic neoplasm kinetics of these cells.
Sample scope Single cell
Release date 2018-09-29
Publication
PubMed ID Article title Journal name DOI Year
30333049 Holo-Seq: single-cell sequencing of holo-transcriptome Genome Biology 10.1186/s13059-018-1553-7 2018
Grants
Agency program Grant ID Grant title
Nature Science Foundation of Zhejiang Province LR15C060001
Ministry of Science and Technology of the People's Republic of China (MOST) National Program on Key Research Project of China 2017YFA0104901
Submitter Zhengyun    Xiao  (xiaozhengyun1993@126.com)
Organization Zhejiang University
Submission date 2018-09-21

Project Data

Resource name Description
BioSample (152) -
SAMC046788 RNA-Seq of Mus musculus: ES Cell
SAMC046787 RNA-Seq of Mus musculus: ES Cell
SAMC046634 RNA-Seq of human sapiens: HEK293T Cell
SAMC046633 RNA-Seq of human sapiens: HEK293T Cell
SAMC046632 RNA-Seq of human sapiens: HEK293T Cell
SAMC046620 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046619 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046618 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046617 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046616 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046615 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046614 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046613 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046612 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046611 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046610 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046609 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046608 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046607 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046606 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046605 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046604 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046603 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046602 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046601 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046600 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046599 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046598 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046597 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046596 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046595 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046594 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046593 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046592 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046591 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046590 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046589 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046588 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046587 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046586 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046585 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046584 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046583 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046582 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046581 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046580 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046579 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046578 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046577 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046576 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046575 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046574 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046573 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046572 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046571 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046570 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046569 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046568 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046567 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046566 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046565 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046564 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046563 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046562 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046561 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046560 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046559 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046558 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046557 scRNA-Seq of human:hepatocellular carcinoma cell
SAMC046556 Exome-capture-Seq of human:MCF7 cell
SAMC046555 scRNA-Seq of human:MCF7 cell
SAMC046554 scRNA-Seq of human:HEK293T cell
SAMC046553 scRNA-Seq of human:HEK293T cell
SAMC046552 scRNA-Seq of human:HEK293T cell
SAMC046551 scRNA-Seq of human:HEK293T cell
SAMC046550 scRNA-Seq of human:HEK293T cell
SAMC046549 scRNA-Seq of human:HEK293T cell
SAMC046631 RNA-Seq of Mus musculus: ES Cell
SAMC046630 RNA-Seq of Mus musculus: ES Cell
SAMC046629 RNA-Seq of Mus musculus: ES Cell
SAMC046628 RNA-Seq of Mus musculus: ES Cell
SAMC046627 RNA-Seq of Mus musculus: ES Cell
SAMC046626 RNA-Seq of Mus musculus: ES Cell
SAMC046625 RNA-Seq of Mus musculus: ES Cell
SAMC046624 RNA-Seq of Mus musculus: ES Cell
SAMC046623 RNA-Seq of Mus musculus: ES Cell
SAMC046622 RNA-Seq of Mus musculus: ES Cell
SAMC046621 RNA-Seq of Mus musculus: ES Cell
SAMC046536 RNA-Seq of Mus musculus: ES Cell
SAMC046535 RNA-Seq of Mus musculus: ES Cell
SAMC046534 scRNA-Seq of Mus musculus: ES Cell
SAMC046533 scRNA-Seq of Mus musculus: ES Cell
SAMC046532 scRNA-Seq of Mus musculus: ES Cell
SAMC046531 scRNA-Seq of Mus musculus: ES Cell
SAMC046530 scRNA-Seq of Mus musculus: ES Cell
SAMC046529 scRNA-Seq of Mus musculus: ES Cell
SAMC046528 scRNA-Seq of Mus musculus: ES Cell
SAMC046527 scRNA-Seq of Mus musculus: ES Cell
SAMC046526 scRNA-Seq of Mus musculus: ES Cell
SAMC046525 scRNA-Seq of Mus musculus: ES Cell
SAMC046524 scRNA-Seq of Mus musculus: ES Cell
SAMC046523 scRNA-Seq of Mus musculus: ES Cell
SAMC046522 scRNA-Seq of Mus musculus: ES Cell
SAMC046521 scRNA-Seq of Mus musculus: ES Cell
SAMC046520 scRNA-Seq of Mus musculus: ES Cell
SAMC046519 scRNA-Seq of Mus musculus: ES Cell
SAMC046518 scRNA-Seq of Mus musculus: ES Cell
SAMC046517 scRNA-Seq of Mus musculus: ES Cell
SAMC046516 scRNA-Seq of Mus musculus: ES Cell
SAMC046515 scRNA-Seq of Mus musculus: ES Cell
SAMC046514 scRNA-Seq of Mus musculus: ES Cell
SAMC046513 scRNA-Seq of Mus musculus: ES Cell
SAMC046512 scRNA-Seq of Mus musculus: ES Cell
SAMC046511 scRNA-Seq of Mus musculus: ES Cell
SAMC046510 scRNA-Seq of Mus musculus: ES Cell
SAMC046509 scRNA-Seq of Mus musculus: ES Cell
SAMC046508 scRNA-Seq of Mus musculus: ES Cell
SAMC046507 RNA-Seq of Mus musculus: ES Cell
SAMC046506 RNA-Seq of Mus musculus: ES Cell
SAMC046505 scRNA-Seq of Mus musculus: ES Cell
SAMC046504 scRNA-Seq of Mus musculus: ES Cell
SAMC046503 scRNA-Seq of Mus musculus: ES Cell
SAMC046502 scRNA-Seq of Mus musculus: ES Cell
SAMC046501 scRNA-Seq of Mus musculus: ES Cell
SAMC046500 scRNA-Seq of Mus musculus: ES Cell
SAMC046499 scRNA-Seq of Mus musculus: ES Cell
SAMC046498 scRNA-Seq of Mus musculus: ES Cell
SAMC046497 scRNA-Seq of Mus musculus: ES Cell
SAMC046496 scRNA-Seq of Mus musculus: ES Cell
SAMC046495 RNA-Seq of Mus musculus: ES Cell
SAMC046494 RNA-Seq of Mus musculus: ES Cell
SAMC046493 scRNA-Seq of Mus musculus: ES Cell
SAMC046492 scRNA-Seq of Mus musculus: ES Cell
SAMC046491 scRNA-Seq of Mus musculus: ES Cell
SAMC046490 scRNA-Seq of Mus musculus: ES Cell
SAMC046489 scRNA-Seq of Mus musculus: ES Cell
SAMC046488 scRNA-Seq of Mus musculus: ES Cell
SAMC046487 scRNA-Seq of Mus musculus: ES Cell
SAMC046486 scRNA-Seq of Mus musculus: ES Cell
SAMC046485 scRNA-Seq of Mus musculus: ES Cell
SAMC046484 scRNA-Seq of Mus musculus: ES Cell
SAMC046483 scRNA-Seq of Mus musculus: ES Cell
SAMC046482 scRNA-Seq of Mus musculus: ES Cell
SAMC046481 scRNA-Seq of Mus musculus: ES Cell
SAMC046480 scRNA-Seq of Mus musculus: ES Cell
SAMC046479 scRNA-Seq of Mus musculus: ES Cell
SAMC046478 scRNA-Seq of Mus musculus: ES Cell
SAMC046477 scRNA-Seq of Mus musculus: ES Cell
SAMC046476 scRNA-Seq of Mus musculus: ES Cell
SAMC046475 scRNA-Seq of Mus musculus: ES Cell
SAMC046474 scRNA-Seq of Mus musculus: ES Cell
SAMC046473 scRNA-Seq of Mus musculus: ES Cell
GSA (2) -
CRA001131 Single-cell sequencing of holo-transcriptome: Mus musculus
CRA001133 Single-cell sequencing of holo-transcriptome: Homo sapiens
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