Accession PRJCA001025
Title ChIP-seq of CBX2 of A549 cell line
Data Types Raw sequence reads
Organisms Homo sapiens
Description The PRC1 complexes regulate gene expression by compacting chromatin and its component CBX2 can bind specifically to the product of PRC2 catalysis, H3K27me3, and functions downstream of PRC2. However, rare data showed the binding profile of CBX2 in cancer cell lines. Here, we show the presence of CBX2 in A549 cell line and demonstrate a role of CBX2 in regulating gene expression in lung adenocarcinoma.
Sample scope Monoisolate
Release date 2019-01-05
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 31822030
Submitter Feifei    Hu  (hufeifei@hust.edu.cn)
Organization Huazhong University of Science and Technology
Submission date 2018-09-07

Project Data

Resource name Description
BioSample (1) -
SAMC046090 CBX2 ChIP-seq of A549 cell
GSA (1) -
CRA001102 ChIP.seq of CBX2 and input in A549 cell
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