Accession PRJCA000999
Title Prevalence and spectrum of AKT1, PIK3CA, PTEN and TP53 somatic mutations in Chinese breast cancer patients
Relevance Medical
Data types Targeted Locus (Loci)
Raw sequence reads
Organisms Homo sapiens
Description Breast cancer is the leading cause of cancer-related death among women. AKT1, PIK3CA, PTEN and TP53 mutations were common observed in breast cancer representing potential clinical biomarkers for breast cancer classification and treatment. In this study, the complete coding regions and exon-intron boundaries of AKT1, PIK3CA, PTEN and TP53 genes were sequenced and analyzed in breast tumor from 313 Chinese breast cancer patients using microfluidic PCR-based target enrichment and next-generation sequencing technology.
Sample scope Multiisolate
Release date 2018-11-01
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81372228
China Hunan Provincial Science and Technology Department 2016GK3022
China Hunan Provincial Science and Technology Department 2016XK2033
China Hunan Provincial Science and Technology Department 2016JC2068
Submitter Ming    Chen  (mingc@sanwaygene.com)
Organization Sanway Gene Technology Inc.
Submission date 2018-08-24

Project Data

Resource name Description