Accession PRJCA000885
Title Znf143 is a regulator of chromatin loop
Relevance Medical
Data types Raw sequence reads
Organisms Homo sapiens
Description We used the siRNA and in situ Hi-C techniques together to validate the effect of Znf143 on chromatin loops. The Znf143 was silenced in HEK293T cells by using siRNA technique, and the in situ Hi-C were performed on both negative control and Znf143-silenced HEK293T cells. The results show that chromatin loops can be both lost and gained after knocking down Znf143 expression level, but the Znf143 silence mainly destabilizes or eliminates chromatin loops.
Sample scope Monoisolate
Release date 2018-05-30
Submitter Zi    Wen  (
Organization Huazhong Agricultural University
Submission date 2018-05-23

Project Data

Resource name Description
BioSample (4) -
SAMC042730 Znf143 siRNA
SAMC042955 Negative control
SAMC042920 Negative control
SAMC042956 Znf143 siRNA
GSA (1) -
CRA000943 Hi-C for HEK293T