Accession PRJCA000834
Title Detection of viral integration events in the patients with HBV infection
Relevance Medical
Data types Raw sequence reads
Genome sequencing
Organisms Hepatitis B virus
Homo sapiens
Description Host genome integration of HBV sequence is considered significant in shaping the immune response to HBV antigens and the development of hepatocellular carcinoma (HCC). Detection and characterization of the integration events in plasma will provide a non-invasive approach for disease monitoring.
Sample scope Multiisolate
Release date 2018-12-31
Publication
PubMed ID Article title Journal name DOI Year
32100258 Noninvasive chimeric DNA profiling identifies tumor-originated HBV integrants contributing to viral antigen expression in liver cancer Hepatology International 10.1007/s12072-020-10016-2 2020
Grants
Agency program Grant ID Grant title
Chinese Academy of Sciences (CAS) 2016098 Dake Zhang
National Natural Science Foundation of China (NSFC) 81201700 Identification of lncRNAs specific to hepatocellular carcinoma in peripheral plood and their functional analysis
Submitter Dake    Zhang  (zhangdk@big.ac.cn)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission date 2018-04-25

Project Data

Resource name Description
BioSample (136)  show -
GSA (1) -
CRA000925 Detection of viral integration events in the patients with HBV infection