Accession PRJCA000812
Title The impact of de novo miRNAs on target genes expression
Relevance Evolution
Data Types Transcriptome or Gene expression
Organisms Drosophila
Description The prevalence of de novo coding genes is controversial due to the length and coding constraints. Non-coding genes, especially small ones, are freer to evolve de novo by comparison. The best examples are microRNAs (miRNAs), a large class of regulatory molecules ~22 nt in length.To study their impact on target gene expression, we dissected testes from miR-984,miR-978 mutant and control flies and performed RNA-seq analysis.
Sample scope Monoisolate
Release date 2018-06-12
PubMed ID Article title Journal name DOI Year
30049791 Death of new microRNA genes in Drosophila via gradual loss of fitness advantages Genome Research 10.1101/gr.233809.117 2018
Submitter Guang-An    Lu  (
Organization SUN YAT-SEN university
Submission date 2018-03-29

Project Data

Resource name Description
BioSample (6) -
SAMC027191 Dmel-mir-984KO-R2
SAMC027190 Dmel-mir-984KO-R1
SAMC027189 Dmel-mir-978KO-R2
SAMC027188 Dmel-mir-978KO-R1
SAMC027187 Control-R2
SAMC027185 Control-R1
GSA (1) -
CRA000857 RNA-seq data of Drosophila de novo miRNA mutants