Accession PRJCA000763
Title MeCP2 Knockout influence reprogramming
Relevance Medical
Data Types Transcriptome or Gene expression
Raw sequence reads
Organisms Mus
Description We utilized CRISPR-Cas9 method to obtain MeCP2 knockout mouse. WT and knockout MEF cells were collected from embyro Day-13.5. The influence of MeCP2 on MEF cells were obtained by RNA-Seq method to study reprogramming process.
Sample scope Monoisolate
Release date 2018-02-09
Publication
PubMed ID Article title Journal name DOI Year
29562294 MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. Journal of Molecular Cell Biology 10.1093/jmcb/mjy018 2018
30245926 Exome sequencing study of 20 patients with high myopia PeerJ 10.7717/peerj.5552 2018
Submitter Wei    Zhang  (zhangweijing226@126.com)
Organization Beijing Institute of Genomics, Chinese Academy of Sciences
Submission date 2018-02-09

Project Data

Resource name Description
BioSample (4) -
SAMC021033 KOMEF2
SAMC021032 KOMEF1
SAMC021031 WTMEF2
SAMC021030 WTMEF1
GSA (1) -
CRA000764 RNA seq data of Mouse WT MEF cells and MeCP2 Knockout cells
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