| Accession |
PRJCA000758 |
| Title |
Transcriptional program in hydroquinone treated-U2OS cells |
| Relevance |
Environmental |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Benzene as a known human cancinogen can directly induce genetic lesion. However, the effect of benzene metabolites on DNA repair has been rarely studied, and the biological mechanisms of that was also unclear. To explore the impact of benzene metabolite on DNA repair, we used human osteosarcoma U2OS cells containing stably integrated repair substrate for homologous repair to be treated with benzene metabolite hydroquinone. |
| Sample scope |
Human cells |
| Release date |
2018-02-10 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 30770924
|
Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-κB pathway
|
Carcinogenesis
|
10.1093/carcin/bgy157
|
2019
|
|
|
| Submitter |
Xuejing
Yang (yangxj@big.ac.cn)
|
| Organization |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| Submission date |
2018-02-08 |
