| Accession |
PRJCA000485 |
| Title |
Splenic microRNA expression profiles and integration analyses involved in host responses to Salmonella enteritidis infection in chickens |
| Relevance |
Agricultural |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Gallus gallus
|
| Description |
To understand the role of miRNAs in regulating genes involved in the host response to Salmonella enteritidis (SE) infection, next generation sequencing was applied to explore the altered splenic expression of microRNAs (miRNAs) and deregulated genes in specific-pathogen-free chickens constituting 3 groups. Birds were either infected or not (controls, C) and those challenged with SE were evaluated 24 h later and separated into 2 groups on the basis of the degree of clinical symptoms and blood load of SE, resistant (R, SE challenged-slight clinical symptoms & < 105 cfu / 10 μL), and susceptible (S, SE challenged-severe clinical symptoms & > 107 cfu / 10 μL) birds |
| Sample scope |
Multiisolate |
| Release date |
2017-07-06 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 28884089
|
Splenic microRNA Expression Profiles and Integration Analyses Involved in Host Responses to Salmonella enteritidis Infection in Chickens.
|
Front Cell Infect Microbiol
|
10.3389/fcimb.2017.00377
|
2017
|
|
|
| Submitter |
PENG
LI (lipengnd@126.com)
|
| Organization |
Institute of Animal Science (IAS), Chinese Academy of Agricultural Sciences (CAAS) |
| Submission date |
2017-07-06 |
