Accession PRJCA000485
Title Splenic microRNA expression profiles and integration analyses involved in host responses to Salmonella enteritidis infection in chickens
Relevance Agricultural
Data types Transcriptome or Gene expression
Organisms Gallus gallus
Description To understand the role of miRNAs in regulating genes involved in the host response to Salmonella enteritidis (SE) infection, next generation sequencing was applied to explore the altered splenic expression of microRNAs (miRNAs) and deregulated genes in specific-pathogen-free chickens constituting 3 groups. Birds were either infected or not (controls, C) and those challenged with SE were evaluated 24 h later and separated into 2 groups on the basis of the degree of clinical symptoms and blood load of SE, resistant (R, SE challenged-slight clinical symptoms & < 105 cfu / 10 μL), and susceptible (S, SE challenged-severe clinical symptoms & > 107 cfu / 10 μL) birds
Sample scope Multiisolate
Release date 2017-07-06
PubMed ID Article title Journal name DOI Year
28884089 Splenic microRNA Expression Profiles and Integration Analyses Involved in Host Responses to Salmonella enteritidis Infection in Chickens. Front Cell Infect Microbiol 10.3389/fcimb.2017.00377 2017
Submitter PENG    LI  (
Organization Institute of Animal Science (IAS), Chinese Academy of Agricultural Sciences (CAAS)
Submission date 2017-07-06

Project Data

Resource name Description
BioSample (1) -
SAMC013229 Chicken Splenic miRNA Transcriptome
GSA (1) -
CRA000315 Samples Disposition for miRNA sequencing