Accession PRJCA000476
Title whole exon sequencing of chemorefractory pediatric AML
Data Types Exome
Organisms Homo sapiens
Description Despite substantial improvement of treatment outcome in pediatric acute myeloid leukemia (AML), chemotherapy resistance remains to be a major concern. While molecular basis behind therapeutic failure was intensely interrogated, genomic alteration of chemotherapy resistance remains poorly characterized in pediatric AML. Here, we performed whole exon sequencing to identify gene mutations associated with primary and secondary chemo-resistance in pediatric AML.
Sample scope Monoisolate
Release date 2017-12-17
PubMed ID Article title Journal name DOI Year
29253671 Whole exome sequencing identifies novel mutations of epigenetic regulators in chemorefractory pediatric acute myeloid leukemia. Leukemia Research 10.1016/j.leukres.2017.12.001 2017
Submitter Di    Zhan  (
Organization Beijing Institute of Genomics
Submission date 2017-06-14

Project Data

Resource name Description
BioSample (46) -
SAMC015224 T21_CTRL
SAMC015223 T21_DIAG
SAMC015222 T20_CTRL
SAMC015221 T20_RELP
SAMC015220 T20_DIAG
SAMC015219 T19_CTRL
SAMC015218 T19_RELP
SAMC015217 T19_DIAG
SAMC015216 T18_CTRL
SAMC015215 T18_DIAG
SAMC015214 T17_CTRL
SAMC015213 T17_RELP
SAMC015212 T17_DIAG
SAMC015211 T16_CTRL
SAMC015210 T16_RELP
SAMC015209 T16_DIAG
SAMC015208 T15_CTRL
SAMC015207 T15_DIAG
SAMC015206 T14_CTRL
SAMC015205 T14_DIAG
SAMC015204 T13_CTRL
SAMC015203 T13_DIAG
SAMC015202 T12_CTRL
SAMC015201 T12_DIAG
SAMC015200 T11_CTRL
SAMC015199 T11_DIAG
SAMC015198 T10_CTRL
SAMC015197 T10_DIAG
SAMC015196 T9_CTRL
SAMC015195 T9_DIAG
SAMC015194 T8_CTRL
SAMC015193 T8_DIAG
SAMC015192 T7_CTRL
SAMC015191 T7_DIAG
SAMC015190 T6_CTRL
SAMC015189 T6_DIAG
SAMC015188 T5_CTRL
SAMC015187 T5_DIAG
SAMC015186 T4_CTRL
SAMC015185 T4_DIAG
SAMC015184 T3_CTRL
SAMC015183 T3_DIAG
SAMC015182 T2_CTRL
SAMC015181 T2_DIAG
SAMC015180 T1_CTRL
SAMC015179 T1_DIAG
GSA (1) -
CRA000332 whole exon sequencing of chemorefractory pediatric AML