Accession PRJCA000416
Title A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte
Data Types Transcriptome or Gene expression
Organisms Homo sapiens
Description Uveal melanoma is the most common primary intraocular tumor in adults in western countries. It is associated with very severe visual morbidity and may lead to distant metastases even after successful treatment of the primary tumor. In order to gain better insight into molecular mechanisms related to tumorigenesis and metastasis of uveal melanoma, we used next-generation sequencing technology (SOLiD, Life Technologies) to acquire global transcriptome alteration between posterior uveal melanoma cells and normal uveal melanocyte.We have identified a large number of potentially interesting genes for biological investigation of uveal melanoma. The expression profiling also provides useful resources for other functional genomic and transcriptome studies.
Sample scope Monoisolate
Release date 2017-04-11
Publication
PubMed ID Article title Journal name DOI Year
10.1371/journal.pone.0016516
Submitter gl    wang  (wanggl@big.ac.cn)
Organization cas
Submission date 2017-04-11

Project Data

Resource name Description
BioSample (2) -
SAMC012646 Normal Uveal Melanocyte
SAMC012645 Uveal Melanoma
GSA (1) -
CRA000233 CRA_233
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