Accession PRJCA000267
Title Global transcriptome analyses of ZIKV infection on mouse
Relevance Medical
Data types Transcriptome or Gene expression
Organisms Mus musculus
Description The suspected link between Zika virus (ZIKV) infection and microcephaly has raised urgent global alarm.To investigate the global impact of ZIKV infection on the whole developing brain at the molecular level, we carried out global transcriptome analyses (RNA-seq). Global gene expression analysis of infected brains reveals the dysregulation of immune response, apoptosis and microcephaly associated genes.
Sample scope Monoisolate
Release date 2016-09-06
Publication
PubMed ID Article title Journal name DOI Year
27179424 Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice Cell Stem Cell 10.1016/j.stem.2016.04.017 2016
Submitter Cui    Li  (licui@genetics.ac.cn)
Organization Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Submission date 2016-09-06

Project Data

Resource name Description
BioSample (4) -
SAMC007002 brain of ZIKV infection
SAMC007001 brain of ZIKV infection
SAMC007000 brain of mock infection
SAMC006999 brain of mock infection
GSA (1) -
CRA000128 CRA_128